Jonathan Collins Selected Research

7-deoxypancratistatin

6/2012	A novel synthetic C-1 analogue of 7-deoxypancratistatin induces apoptosis in p53 positive and negative human colorectal cancer cells by targeting the mitochondria: enhancement of activity by tamoxifen.
5/2012	Enhancement of apoptotic and autophagic induction by a novel synthetic C-1 analogue of 7-deoxypancratistatin in human breast adenocarcinoma and neuroblastoma cells with tamoxifen.
1/2011	Selective cytotoxicity against human osteosarcoma cells by a novel synthetic C-1 analogue of 7-deoxypancratistatin is potentiated by curcumin.

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Jonathan Collins Research Topics

Disease

5	Neoplasms (Cancer) 07/2018 - 05/2010
1	Heart Failure 02/2019
1	Body Weight (Weight, Body) 02/2019
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 02/2019
1	Colorectal Neoplasms (Colorectal Cancer) 06/2012
1	Breast Neoplasms (Breast Cancer) 05/2012
1	Neuroblastoma 05/2012
1	Adenocarcinoma 05/2012
1	Osteosarcoma (Osteogenic Sarcoma) 01/2011

Drug/Important Bio-Agent (IBA)

4	pancratistatinIBA 07/2018 - 01/2011
3	7-deoxypancratistatinIBA 06/2012 - 01/2011
3	JCTH-4IBA 06/2012 - 01/2011
2	Tamoxifen FDA LinkGeneric 06/2012 - 05/2012
1	Carbon DioxideIBA 02/2019
1	CurcuminIBA 01/2011
1	Matrix Metalloproteinases (MMPs)IBA 01/2011
1	Apoptosis Inducing FactorIBA 01/2011
1	endonuclease GIBA 01/2011
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2011
1	Biological ProductsIBA 05/2010
1	AldehydesIBA 05/2010

Therapy/Procedure

2	Therapeutics 06/2012 - 05/2012
1	Artificial Respiration (Mechanical Ventilation) 02/2019
1	Drug Therapy (Chemotherapy) 05/2012